Union County blanked Greene Coutny 42-0 on Friday in Blairsville.
Chase Barnett scored three touchdowns to lead the Panthers.
Quarterback Joseph Mancuso finished 12 of 20 passing for 215 yards and a pair of scores caught by Robert Prunier and Jacob Rogers. Rogers led the Union County receiving corps with 142 yards on six catches.
Nick Whittle paced the ground attack with 106 yards and a touchdown on 18 carries, and Mancuso added 100 yards on 11 carries.
The Panthers (5-2, 3-1 Region 8-AA) tallied 459 yards of total offense.
Union County plays host to Rabun County on Friday in Blairsville.