Five men have been charged with drug trafficking in an operation that wound up in Gainesville and resulted in the seizure of 1,572 pounds of marijuana with an estimated street value of $3.14 million. “This is our largest marijuana bust in probably 10 years,” said Hall County Sheriff’s Lt. Scott Ware, commander of the Gainesville-Hall County Multi-Agency Narcotics Squad, speaking Tuesday morning in a press conference at the Gainesville Justice Center. The investigation began several weeks before the April 12 arrests on information developed by the U.S. Immigration and Customs Enforcement, which is the main investigative arm of the Department of Homeland Security.